Different Effects of Metformin and A769662 on Sodium Iodate-Induced Cytotoxicity in Retinal Pigment Epithelial Cells: Distinct Actions on Mitochondrial Fission and Respiration

Oxidative stress-associated retinal pigment epithelium (RPE) cell death is critically implicated in the pathogenesis of visual dysfunction and blindness of retinal degenerative diseases. Sodium iodate (NaIO(3)) is an oxidative retinotoxin and causes RPE damage. Previously, we found that NaIO(3) can...

Descripción completa

Detalles Bibliográficos
Autores principales: Chan, Chi-Ming, Sekar, Ponarulselvam, Huang, Duen-Yi, Hsu, Shu-Hao, Lin, Wan-Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693507/
https://www.ncbi.nlm.nih.gov/pubmed/33126710
http://dx.doi.org/10.3390/antiox9111057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693507/
https://www.ncbi.nlm.nih.gov/pubmed/33126710
http://dx.doi.org/10.3390/antiox9111057

Ejemplares similares