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Development of a Curcumin-Loaded Polymeric Microparticulate Oral Drug Delivery System for Colon Targeting by Quality-by-Design Approach

The purpose of this study was to apply the quality-by-design (QbD) approach for the development of colon-targeted curcumin-loaded polymeric microparticles (Col-CUR-MPs). The proportion of the enterosoluble polymer (Eudragit(®) FS) in the polymeric matrix, curcumin concentration, and the concentratio...

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Detalles Bibliográficos
Autores principales: Hales, Dana, Tefas, Lucia Ruxandra, Tomuță, Ioan, Moldovan, Cristian, Gulei, Diana, Munteanu, Raluca, Porfire, Alina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693510/
https://www.ncbi.nlm.nih.gov/pubmed/33121175
http://dx.doi.org/10.3390/pharmaceutics12111027