Multiple imputation and direct estimation for qPCR data with non-detects

BACKGROUND: Quantitative real-time PCR (qPCR) is one of the most widely used methods to measure gene expression. An important aspect of qPCR data that has been largely ignored is the presence of non-detects: reactions failing to exceed the quantification threshold and therefore lacking a measurement...

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Detalles Bibliográficos
Autores principales: Sherina, Valeriia, McMurray, Helene R., Powers, Winslow, Land, Harmut, Love, Tanzy M. T., McCall, Matthew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693525/
https://www.ncbi.nlm.nih.gov/pubmed/33243147
http://dx.doi.org/10.1186/s12859-020-03807-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693525/
https://www.ncbi.nlm.nih.gov/pubmed/33243147
http://dx.doi.org/10.1186/s12859-020-03807-9

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