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Multiple imputation and direct estimation for qPCR data with non-detects
BACKGROUND: Quantitative real-time PCR (qPCR) is one of the most widely used methods to measure gene expression. An important aspect of qPCR data that has been largely ignored is the presence of non-detects: reactions failing to exceed the quantification threshold and therefore lacking a measurement...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693525/ https://www.ncbi.nlm.nih.gov/pubmed/33243147 http://dx.doi.org/10.1186/s12859-020-03807-9 |