Effects of Netarsudil on Actin-Driven Cellular Functions in Normal and Glaucomatous Trabecular Meshwork Cells: A Live Imaging Study

The actin cytoskeleton of trabecular meshwork (TM) cells is a therapeutic target for lowering intraocular pressure (IOP) in glaucoma patients. Netarsudil (the active ingredient in Rhopressa(TM)) is a Rho-associated protein kinase inhibitor that induces disassembly of actin stress fibers. Here, we us...

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Detalles Bibliográficos
Autores principales: Keller, Kate E., Kopczynski, Casey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693753/
https://www.ncbi.nlm.nih.gov/pubmed/33142742
http://dx.doi.org/10.3390/jcm9113524

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693753/
https://www.ncbi.nlm.nih.gov/pubmed/33142742
http://dx.doi.org/10.3390/jcm9113524

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