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Effects of Netarsudil on Actin-Driven Cellular Functions in Normal and Glaucomatous Trabecular Meshwork Cells: A Live Imaging Study
The actin cytoskeleton of trabecular meshwork (TM) cells is a therapeutic target for lowering intraocular pressure (IOP) in glaucoma patients. Netarsudil (the active ingredient in Rhopressa(TM)) is a Rho-associated protein kinase inhibitor that induces disassembly of actin stress fibers. Here, we us...
Autores principales: | Keller, Kate E., Kopczynski, Casey |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693753/ https://www.ncbi.nlm.nih.gov/pubmed/33142742 http://dx.doi.org/10.3390/jcm9113524 |
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