Overexpression of α-Synuclein by Oligodendrocytes in Transgenic Mice Does Not Recapitulate the Fibrillar Aggregation Seen in Multiple System Atrophy

The synucleinopathy underlying multiple system atrophy (MSA) is characterized by the presence of abundant amyloid inclusions containing fibrillar α-synuclein (α-syn) aggregates in the brains of the patients and is associated with an extensive neurodegeneration. In contrast to Parkinson’s disease (PD...

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Detalles Bibliográficos
Autores principales: Laferrière, Florent, He, Xin, Zinghirino, Federica, Doudnikoff, Evelyne, Faggiani, Emilie, Meissner, Wassilios G., Bezard, Erwan, De Giorgi, Francesca, Ichas, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693764/
https://www.ncbi.nlm.nih.gov/pubmed/33138150
http://dx.doi.org/10.3390/cells9112371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693764/
https://www.ncbi.nlm.nih.gov/pubmed/33138150
http://dx.doi.org/10.3390/cells9112371

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