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Investigation of Genetic Modifiers of Copper Toxicosis in Labrador Retrievers

Copper toxicosis is a complex genetic disorder in Labrador retrievers characterized by hepatic copper accumulation eventually leading to liver cirrhosis. The variation of hepatic copper levels in Labrador retrievers has been partly explained by mutations in ATP7A c.980C>T and ATP7B c.4358G>A....

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Detalles Bibliográficos
Autores principales: Wu, Xiaoyan, den Boer, Elise R., Vos-Loohuis, Manon, van Steenbeek, Frank G., Monroe, Glen R., Nijman, Isaäc J., Leegwater, Peter. A. J., Fieten, Hille
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693796/
https://www.ncbi.nlm.nih.gov/pubmed/33142854
http://dx.doi.org/10.3390/life10110266