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Investigation of Genetic Modifiers of Copper Toxicosis in Labrador Retrievers
Copper toxicosis is a complex genetic disorder in Labrador retrievers characterized by hepatic copper accumulation eventually leading to liver cirrhosis. The variation of hepatic copper levels in Labrador retrievers has been partly explained by mutations in ATP7A c.980C>T and ATP7B c.4358G>A....
Autores principales: | Wu, Xiaoyan, den Boer, Elise R., Vos-Loohuis, Manon, van Steenbeek, Frank G., Monroe, Glen R., Nijman, Isaäc J., Leegwater, Peter. A. J., Fieten, Hille |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693796/ https://www.ncbi.nlm.nih.gov/pubmed/33142854 http://dx.doi.org/10.3390/life10110266 |
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