Therapeutic Efficacy of GC1118, a Novel Anti-EGFR Antibody, against Glioblastoma with High EGFR Amplification in Patient-Derived Xenografts

SIMPLE SUMMARY: GC1118 is a novel anti-EGFR monoclonal antibody with a distinct mode of epitope binding. Its therapeutic efficacy has been validated in preclinical studies of several cancers. We evaluated the anti-tumor efficacy of GC1118 against glioblastoma (GBM) using patient-derived xenografts (...

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Detalles Bibliográficos
Autores principales: Lee, Kyoungmin, Koo, Harim, Kim, Yejin, Kim, Donggeon, Son, Eunju, Yang, Heekyoung, Lim, Yangmi, Hur, Minkyu, Lee, Hye Won, Choi, Seung Won, Nam, Do-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693807/
https://www.ncbi.nlm.nih.gov/pubmed/33142709
http://dx.doi.org/10.3390/cancers12113210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693807/
https://www.ncbi.nlm.nih.gov/pubmed/33142709
http://dx.doi.org/10.3390/cancers12113210

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