Unveiling the Hidden Treasury: CIITA-Driven MHC Class II Expression in Tumor Cells to Dig up the Relevant Repertoire of Tumor Antigens for Optimal Stimulation of Tumor Specific CD4+ T Helper Cells

SIMPLE SUMMARY: It is becoming clear that combined approaches are required to fight and succeed against cancer. As far as immune-based strategies, new generation anti-tumor vaccines will certainly play a crucial role. A key aspect is to identify tumor antigens which optimally stimulate CD4+ T helper...

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Detalles Bibliográficos
Autores principales: Forlani, Greta, Shallak, Mariam, Celesti, Fabrizio, Accolla, Roberto S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693840/
https://www.ncbi.nlm.nih.gov/pubmed/33138029
http://dx.doi.org/10.3390/cancers12113181

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693840/
https://www.ncbi.nlm.nih.gov/pubmed/33138029
http://dx.doi.org/10.3390/cancers12113181

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