Vadadustat, a HIF Prolyl Hydroxylase Inhibitor, Improves Immunomodulatory Properties of Human Mesenchymal Stromal Cells

The therapeutic potential of mesenchymal stromal cells (MSCs) is largely attributed to their immunomodulatory properties, which can be further improved by hypoxia priming. In this study, we investigated the immunomodulatory properties of MSCs preconditioned with hypoxia-mimetic Vadadustat (AKB-6548,...

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Detalles Bibliográficos
Autores principales: Zielniok, Katarzyna, Burdzinska, Anna, Kaleta, Beata, Zagozdzon, Radoslaw, Paczek, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693843/
https://www.ncbi.nlm.nih.gov/pubmed/33139632
http://dx.doi.org/10.3390/cells9112396

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693843/
https://www.ncbi.nlm.nih.gov/pubmed/33139632
http://dx.doi.org/10.3390/cells9112396

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