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Liquid Crystalline Nanoparticles for Nasal Delivery of Rosuvastatin: Implications on Therapeutic Efficacy in Management of Epilepsy

In the present study we investigated the protective role of intranasal rosuvastatin liquid crystalline nanoparticles (Ros-LCNPs) against pentylenetetrazole (PTZ) induced seizures, increasing current electroshock (ICES) induced seizures, and PTZ-induced status epilepticus. From the dose titration stu...

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Detalles Bibliográficos
Autores principales: Ahmed, Mohammad Zubair, Khan, Urooj A., Haye, Abdul, Agarwal, Nidhi B., Alhakamy, Nabil A., Alhadrami, Hani A., Warsi, Musarrat Husain, Jain, Gaurav K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693896/
https://www.ncbi.nlm.nih.gov/pubmed/33143084
http://dx.doi.org/10.3390/ph13110356