Bioavailability Improvement of Carbamazepine via Oral Administration of Modified-Release Amorphous Solid Dispersions in Rats

The purpose of this study was to improve the bioavailability of carbamazepine (CBZ), a poorly water-soluble antiepileptic drug, via modified-release amorphous solid dispersions (mr-ASD) by a thin film freezing (TFF) process. Three types of CBZ-mr-ASD with immediate-, delayed-, and controlled-release...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Houli, Zhang, Meimei, Xiong, Lilong, Feng, Weiyi, Williams, Robert O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693946/
https://www.ncbi.nlm.nih.gov/pubmed/33114739
http://dx.doi.org/10.3390/pharmaceutics12111023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693946/
https://www.ncbi.nlm.nih.gov/pubmed/33114739
http://dx.doi.org/10.3390/pharmaceutics12111023

Ejemplares similares