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Bioavailability Improvement of Carbamazepine via Oral Administration of Modified-Release Amorphous Solid Dispersions in Rats

The purpose of this study was to improve the bioavailability of carbamazepine (CBZ), a poorly water-soluble antiepileptic drug, via modified-release amorphous solid dispersions (mr-ASD) by a thin film freezing (TFF) process. Three types of CBZ-mr-ASD with immediate-, delayed-, and controlled-release...

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Detalles Bibliográficos
Autores principales:	Li, Houli, Zhang, Meimei, Xiong, Lilong, Feng, Weiyi, Williams, Robert O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693946/ https://www.ncbi.nlm.nih.gov/pubmed/33114739 http://dx.doi.org/10.3390/pharmaceutics12111023

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