Cargando…

Anti-Inflammatory Activity of a Cyclic Tetrapeptide in Mouse and Human Experimental Models

A cyclic tetrapeptide Pro-Pro-Pheβ(3)ho-Phe (4B8M) was tested for immunosuppressive activity and potential therapeutic utility in several in vitro and in vivo mouse and human models. The tetrapeptide was less toxic for mouse splenocytes in comparison to cyclosporine A (CsA) and a parent cyclolinopep...

Descripción completa

Detalles Bibliográficos
Autores principales: Zimecki, Michał, Artym, Jolanta, Kałas, Wojciech, Strządała, Leon, Kaleta-Kuratewicz, Katarzyna, Kuryszko, Jan, Kaszuba, Andrzej, Kaczmarek, Krzysztof, Zabrocki, Janusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7693979/
https://www.ncbi.nlm.nih.gov/pubmed/33126725
http://dx.doi.org/10.3390/pharmaceutics12111030