Glycyrrhetinic Acid-Functionalized Mesoporous Silica Nanoparticles for the Co-Delivery of DOX/CPT-PEG for Targeting HepG2 Cells

A pH-triggered mesoporous silica nanoparticle (MSN)-based nano-vehicle for the dual delivery of doxorubicin (DOX)/camptothecin-PEG (CPT-PEG) has been prepared. To enhance its selectivity, the nanoparticles were decorated with glycyrrhetinic acid (GA) to target HepG2 cells. The highly insoluble CPT w...

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Detalles Bibliográficos
Autores principales: Martínez-Edo, Gabriel, Fornaguera, Cristina, Borrós, Salvador, Sánchez-García, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694026/
https://www.ncbi.nlm.nih.gov/pubmed/33147860
http://dx.doi.org/10.3390/pharmaceutics12111048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694026/
https://www.ncbi.nlm.nih.gov/pubmed/33147860
http://dx.doi.org/10.3390/pharmaceutics12111048

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