The Effects of Single Nucleotide Polymorphisms in Cancer RNAi Therapies

SIMPLE SUMMARY: Despite the recent progress in RNAi delivery of siRNA-based therapeutics for cancer therapy, the presence of single nucleotide polymorphisms (SNPs) in the general population could dramatically reduce the effectiveness of RNAi therapy. Their ubiquitous presence can also lead to unpred...

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Detalles Bibliográficos
Autores principales: Gebert, Magdalena, Jaśkiewicz, Maciej, Moszyńska, Adrianna, Collawn, James F., Bartoszewski, Rafał
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694039/
https://www.ncbi.nlm.nih.gov/pubmed/33113880
http://dx.doi.org/10.3390/cancers12113119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694039/
https://www.ncbi.nlm.nih.gov/pubmed/33113880
http://dx.doi.org/10.3390/cancers12113119

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