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The Effects of Single Nucleotide Polymorphisms in Cancer RNAi Therapies
SIMPLE SUMMARY: Despite the recent progress in RNAi delivery of siRNA-based therapeutics for cancer therapy, the presence of single nucleotide polymorphisms (SNPs) in the general population could dramatically reduce the effectiveness of RNAi therapy. Their ubiquitous presence can also lead to unpred...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694039/ https://www.ncbi.nlm.nih.gov/pubmed/33113880 http://dx.doi.org/10.3390/cancers12113119 |