LDOC1 Suppresses Microbe-Induced Production of IL-1β in Human Normal and Cancerous Oral Cells through the PI3K/Akt/GSK-3β Axis

SIMPLE SUMMARY: Oral microbes often proliferate due to poor oral hygiene (POH). POH is associated with OSCC (oral squamous cell carcinoma). We investigated the role of LDOC1 in the production of IL-1β, an oncogenic proinflammatory cytokine in OSCC, induced by microorganisms in human oral cells. Cand...

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Detalles Bibliográficos
Autores principales: Lee, Chia-Huei, Hung, Pin-Feng, Liu, Ko-Jiunn, Chung, Hsuan-Lien, Yang, Wen-Chan, Hsu, Kai-Cheng, Fong, Tsorng-Harn, Lo, Hsiu-Jung, Chen, Ya-Ping, Yang, Ji-Rui, Yen, Ching-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694066/
https://www.ncbi.nlm.nih.gov/pubmed/33120999
http://dx.doi.org/10.3390/cancers12113148

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694066/
https://www.ncbi.nlm.nih.gov/pubmed/33120999
http://dx.doi.org/10.3390/cancers12113148

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