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Amino Acid k-mer Feature Extraction for Quantitative Antimicrobial Resistance (AMR) Prediction by Machine Learning and Model Interpretation for Biological Insights

SIMPLE SUMMARY: Infectious bacteria (microbes) are able to evolve to become resistant to antibiotics (develop antimicrobial resistance, or AMR). Resistant microbes are harder to treat, requiring higher doses, or alternative medications, which can be more toxic. Because of inappropriate use of medici...

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Detalles Bibliográficos
Autores principales: ValizadehAslani, Taha, Zhao, Zhengqiao, Sokhansanj, Bahrad A., Rosen, Gail L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694136/
https://www.ncbi.nlm.nih.gov/pubmed/33126516
http://dx.doi.org/10.3390/biology9110365