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WNT11-Conditioned Medium Promotes Angiogenesis through the Activation of Non-Canonical WNT-PKC-JNK Signaling Pathway

Background: We demonstrated that the transduction of Wnt11 into mesenchymal stem cells (MSCs) (MSC(Wnt11)) promotes these cells differentiation into cardiac phenotypes. In the present study, we investigated the paracrine effects of MSC(Wnt11) on cardiac function and angiogenesis. Methods and Results...

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Detalles Bibliográficos
Autores principales: Wang, Jingcai, Gong, Min, Zuo, Shi, Xu, Jie, Paul, Chris, Li, Hongxia, Liu, Min, Wang, Yi-Gang, Ashraf, Muhammad, Xu, Meifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694138/
https://www.ncbi.nlm.nih.gov/pubmed/33137935
http://dx.doi.org/10.3390/genes11111277