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Improving Radiation Response in Glioblastoma Using ECO/siRNA Nanoparticles Targeting DNA Damage Repair

SIMPLE SUMMARY: Glioblastoma (GBM) is the most common form of brain cancer and among the most lethal of human cancers. Radiation therapy is a mainstay in the standard of care for GBM, killing tumor cells by creating DNA damage. Inhibiting DNA damage repair (DDR) proteins enhances radiation therapy b...

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Detalles Bibliográficos
Autores principales: Lee, Jennifer A., Ayat, Nadia, Sun, Zhanhu, Tofilon, Philip J., Lu, Zheng-Rong, Camphausen, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694254/
https://www.ncbi.nlm.nih.gov/pubmed/33158243
http://dx.doi.org/10.3390/cancers12113260