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Human Adipose Tissue-Derived Stromal Cells Suppress Human, but Not Murine Lymphocyte Proliferation, via Indoleamine 2,3-Dioxygenase Activity

Over recent years, mesenchymal stromal cells (MSC) have gained immense attraction in immunotherapy, regenerative medicine and tissue engineering. MSC microenvironment modulation occurs through synergy of direct cell–cell contact, and secreted soluble factors and extracellular vesicles (EV). MSC-deri...

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Detalles Bibliográficos
Autores principales: Torres Crigna, Adriana, Uhlig, Stefanie, Elvers-Hornung, Susanne, Klüter, Harald, Bieback, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694333/
https://www.ncbi.nlm.nih.gov/pubmed/33167329
http://dx.doi.org/10.3390/cells9112419