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Simultaneous Tumor and Stroma Targeting by Oncolytic Viruses

Current cancer therapeutics often insufficiently eradicate malignant cells due to the surrounding dense tumor stroma. This multi-componential tissue consists of mainly cancer-associated fibroblasts, the (compact) extracellular matrix, tumor vasculature, and tumor-associated macrophages, which all ex...

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Detalles Bibliográficos
Autores principales: Everts, Anne, Bergeman, Melissa, McFadden, Grant, Kemp, Vera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694393/
https://www.ncbi.nlm.nih.gov/pubmed/33167307
http://dx.doi.org/10.3390/biomedicines8110474