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Controlling the Switch from Neurogenesis to Pluripotency during Marmoset Monkey Somatic Cell Reprogramming with Self-Replicating mRNAs and Small Molecules

Induced pluripotent stem cells (iPSCs) hold enormous potential for the development of cell-based therapies; however, the safety and efficacy of potential iPSC-based treatments need to be verified in relevant animal disease models before their application in the clinic. Here, we report the derivation...

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Detalles Bibliográficos
Autores principales: Petkov, Stoyan, Dressel, Ralf, Rodriguez-Polo, Ignacio, Behr, Rüdiger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694496/
https://www.ncbi.nlm.nih.gov/pubmed/33167468
http://dx.doi.org/10.3390/cells9112422