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Performance and Stability of Tenofovir Alafenamide Formulations within Subcutaneous Biodegradable Implants for HIV Pre-Exposure Prophylaxis (PrEP)

A critical need exists to develop diverse biomedical strategies for the widespread use of HIV Pre-Exposure Prophylaxis (HIV PrEP). This manuscript describes a subcutaneous reservoir-style implant for long-acting delivery of tenofovir alafenamide (TAF) for HIV PrEP. We detail key parameters of the TA...

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Detalles Bibliográficos
Autores principales: Li, Linying, Johnson, Leah M., Krovi, Sai Archana, Demkovich, Zach R., van der Straten, Ariane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694512/
https://www.ncbi.nlm.nih.gov/pubmed/33167509
http://dx.doi.org/10.3390/pharmaceutics12111057