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HIV-1 promoter is gradually silenced when integrated into BACH2 in Jurkat T-cells
BACKGROUND: The persistence of the latent HIV-1 reservoir is a major obstacle to curing HIV-1 infection. HIV-1 integrates into the cellular genome and some targeted genomic loci are frequently detected in clonally expanded latently HIV-1 infected cells, for instance, the gene BTB domain and CNC homo...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694569/ https://www.ncbi.nlm.nih.gov/pubmed/33282555 http://dx.doi.org/10.7717/peerj.10321 |