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Mendelian randomization study shows no causal effects of serum urate levels on the risk of MS
OBJECTIVE: To examine whether lifelong genetically increased serum urate levels, a potent antioxidant, contribute to MS susceptibility using Mendelian randomization (MR). METHODS: This 2-sample MR study included 25 independent genetic variants strongly associated with serum urate levels in a genome-...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694579/ https://www.ncbi.nlm.nih.gov/pubmed/33214142 http://dx.doi.org/10.1212/NXI.0000000000000920 |