The Immune Checkpoint PD-1 in Natural Killer Cells: Expression, Function and Targeting in Tumour Immunotherapy

SIMPLE SUMMARY: Natural killer cells are innate cytotoxic lymphocytes that play a key role in the anti-tumor immune response. In the tumor microenvironment, however, the effector functions of these cells are often impaired by the induction of inhibitory surface molecules, including PD-1. In the pres...

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Detalles Bibliográficos
Autores principales: Quatrini, Linda, Mariotti, Francesca Romana, Munari, Enrico, Tumino, Nicola, Vacca, Paola, Moretta, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694632/
https://www.ncbi.nlm.nih.gov/pubmed/33172030
http://dx.doi.org/10.3390/cancers12113285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694632/
https://www.ncbi.nlm.nih.gov/pubmed/33172030
http://dx.doi.org/10.3390/cancers12113285

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