Functional Expression of All Human Sulfotransferases in Fission Yeast, Assay Development, and Structural Models for Isoforms SULT4A1 and SULT6B1

Cytosolic sulfotransferases (SULTs) catalyze phase II (conjugation) reactions of drugs and endogenous compounds. A complete set of recombinant fission yeast strains each expressing one of the 14 human SULTs was generated, including SULT4A1 and SULT6B1. Sulfation of test substrates by whole-cell biot...

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Detalles Bibliográficos
Autores principales: Sun, Yanan, Machalz, David, Wolber, Gerhard, Parr, Maria Kristina, Bureik, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694633/
https://www.ncbi.nlm.nih.gov/pubmed/33171978
http://dx.doi.org/10.3390/biom10111517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694633/
https://www.ncbi.nlm.nih.gov/pubmed/33171978
http://dx.doi.org/10.3390/biom10111517

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