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In Situ Detection of Complex DNA Damage Using Microscopy: A Rough Road Ahead

SIMPLE SUMMARY: We comparatively discuss all possible methodologies for the complex DNA damage in situ detection. Fluorescent microscopy (FM) is the universal approach utilized in every technique, thus we discuss several FM variants. As image colocalization analysis is involved in the majority of me...

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Detalles Bibliográficos
Autores principales: Nikitaki, Zacharenia, Pariset, Eloise, Sudar, Damir, Costes, Sylvain V., Georgakilas, Alexandros G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694657/
https://www.ncbi.nlm.nih.gov/pubmed/33172046
http://dx.doi.org/10.3390/cancers12113288