AMPKα1 Regulates Lung and Breast Cancer Progression by Regulating TLR4-Mediated TRAF6-BECN1 Signaling Axis

SIMPLE SUMMARY: TRAF6-BECN1 signaling axis in TLR4 signal plays an essential role for the autophagy induction, thereby it regulates cancer migration and invasion. Here we show that AMPKα1, one of the isoforms of AMPK, is functionally involved in autophagy induction by regulating the TRAF6-BECN1 sign...

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Detalles Bibliográficos
Autores principales: Kim, Mi-Jeong, Min, Yoon, Son, Juhee, Kim, Ji Young, Lee, Ji Su, Kim, Duk-Hwan, Lee, Ki-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694660/
https://www.ncbi.nlm.nih.gov/pubmed/33172060
http://dx.doi.org/10.3390/cancers12113289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694660/
https://www.ncbi.nlm.nih.gov/pubmed/33172060
http://dx.doi.org/10.3390/cancers12113289

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