JSRV Intragenic Enhancer Element Increases Expression from a Heterologous Promoter and Promotes High Level AAV-Mediated Transgene Expression in the Lung and Liver of Mice

Jaagsiekte sheep retrovirus (JSRV) induces tumors in the distal airways of sheep and goats. A putative intragenic enhancer, termed JE, localized to the 3′ end of the JSRV env gene, has been previously described. Herein we provide further evidence that the JE functions as a transcriptional enhancer,...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Darrick L., Chow, Natalie, Wootton, Sarah K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694761/
https://www.ncbi.nlm.nih.gov/pubmed/33172105
http://dx.doi.org/10.3390/v12111266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694761/
https://www.ncbi.nlm.nih.gov/pubmed/33172105
http://dx.doi.org/10.3390/v12111266

Ejemplares similares