Cargando…

Mechanisms of Ras Membrane Organization and Signaling: Ras Rocks Again

Ras is the most frequently mutated oncogene and recent drug development efforts have spurred significant new research interest. Here we review progress toward understanding how Ras functions in nanoscale, proteo-lipid signaling complexes on the plasma membrane, called nanoclusters. We discuss how G-...

Descripción completa

Detalles Bibliográficos
Autores principales: Abankwa, Daniel, Gorfe, Alemayehu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694788/
https://www.ncbi.nlm.nih.gov/pubmed/33172116
http://dx.doi.org/10.3390/biom10111522