Population genetic analysis of the Plasmodium falciparum circumsporozoite protein in two distinct ecological regions in Ghana

BACKGROUND: Extensive genetic diversity in the Plasmodium falciparum circumsporozoite protein (PfCSP) is a major contributing factor to the moderate efficacy of the RTS,S/AS01 vaccine. The transmission intensity and rates of recombination within and between populations influence the extent of its ge...

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Detalles Bibliográficos
Autores principales: Amegashie, Elikplim A., Amenga-Etego, Lucas, Adobor, Courage, Ogoti, Peter, Mbogo, Kevin, Amambua-Ngwa, Alfred, Ghansah, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694917/
https://www.ncbi.nlm.nih.gov/pubmed/33246470
http://dx.doi.org/10.1186/s12936-020-03510-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7694917/
https://www.ncbi.nlm.nih.gov/pubmed/33246470
http://dx.doi.org/10.1186/s12936-020-03510-3

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