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Angiotensin II-Induced Cardiovascular Fibrosis Is Attenuated by NO-Sensitive Guanylyl Cyclase1

In the NO/cGMP signaling cascade, relevant in the cardiovascular system, two NO-sensitive guanylyl cyclase (NO-GC) isoforms are responsible for NO-dependent cGMP generation. Here, the impact of the major NO-GC isoform, NO-GC1, on fibrosis development in the cardiovascular system was studied in NO-GC...

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Detalles Bibliográficos
Autores principales: Broekmans, Kathrin, Giesen, Jan, Menges, Lukas, Koesling, Doris, Russwurm, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695185/
https://www.ncbi.nlm.nih.gov/pubmed/33171621
http://dx.doi.org/10.3390/cells9112436