The Importance of Poly(ethylene glycol) and Lipid Structure in Targeted Gene Delivery to Lymph Nodes by Lipid Nanoparticles

Targeted delivery of nucleic acids to lymph nodes is critical for the development of effective vaccines and immunotherapies. However, it remains challenging to achieve selective lymph node delivery. Current gene delivery systems target mainly to the liver and typically exhibit off-target transfectio...

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Detalles Bibliográficos
Autores principales: Zukancic, Danijela, Suys, Estelle J. A., Pilkington, Emily H., Algarni, Azizah, Al-Wassiti, Hareth, Truong, Nghia P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695259/
https://www.ncbi.nlm.nih.gov/pubmed/33182382
http://dx.doi.org/10.3390/pharmaceutics12111068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695259/
https://www.ncbi.nlm.nih.gov/pubmed/33182382
http://dx.doi.org/10.3390/pharmaceutics12111068

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