Silymarin Inhibits Glutamate Release and Prevents against Kainic Acid-Induced Excitotoxic Injury in Rats

Silymarin, a polyphenoic flavonoid derived from the seeds of milk thistle (Silybum marianum), exhibits neuroprotective effects. In this study, we used a model of rat cerebrocortical synaptosomes to investigate whether silymarin affects the release of glutamate, an essential neurotransmitter involved...

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Detalles Bibliográficos
Autores principales: Lu, Cheng-Wei, Lin, Tzu-Yu, Chiu, Kuan-Ming, Lee, Ming-Yi, Huang, Jih-Hsin, Wang, Su-Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695262/
https://www.ncbi.nlm.nih.gov/pubmed/33182349
http://dx.doi.org/10.3390/biomedicines8110486

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695262/
https://www.ncbi.nlm.nih.gov/pubmed/33182349
http://dx.doi.org/10.3390/biomedicines8110486

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