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Silymarin Inhibits Glutamate Release and Prevents against Kainic Acid-Induced Excitotoxic Injury in Rats
Silymarin, a polyphenoic flavonoid derived from the seeds of milk thistle (Silybum marianum), exhibits neuroprotective effects. In this study, we used a model of rat cerebrocortical synaptosomes to investigate whether silymarin affects the release of glutamate, an essential neurotransmitter involved...
Autores principales: | Lu, Cheng-Wei, Lin, Tzu-Yu, Chiu, Kuan-Ming, Lee, Ming-Yi, Huang, Jih-Hsin, Wang, Su-Jane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695262/ https://www.ncbi.nlm.nih.gov/pubmed/33182349 http://dx.doi.org/10.3390/biomedicines8110486 |
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