Induction of Durable Antitumor Response by a Novel Oncolytic Herpesvirus Expressing Multiple Immunomodulatory Transgenes

Oncolytic virotherapy is a promising new tool for cancer treatment, but direct lytic destruction of tumor cells is not sufficient and must be accompanied by strong immune activation to elicit anti-tumor immunity. We report here the creation of a novel replication-competent recombinant oncolytic herp...

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Detalles Bibliográficos
Autores principales: Chouljenko, Dmitry V., Ding, Jun, Lee, I-Fang, Murad, Yanal M., Bu, Xuexian, Liu, Guoyu, Delwar, Zahid, Sun, Yi, Yu, Sheng, Samudio, Ismael, Zhao, Ronghua, Jia, William Wei-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695276/
https://www.ncbi.nlm.nih.gov/pubmed/33182232
http://dx.doi.org/10.3390/biomedicines8110484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695276/
https://www.ncbi.nlm.nih.gov/pubmed/33182232
http://dx.doi.org/10.3390/biomedicines8110484

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