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BR-BCSC Signature: The Cancer Stem Cell Profile Enriched in Brain Metastases that Predicts a Worse Prognosis in Lymph Node-Positive Breast Cancer

Brain metastases remain an unmet clinical need in breast oncology, being frequently found in HER2-overexpressing and triple-negative carcinomas. These tumors were reported to be highly cancer stem-like cell-enriched, suggesting that brain metastases probably arise by the seeding of cancer cells with...

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Detalles Bibliográficos
Autores principales: Dionísio, Maria Rita, Vieira, André F., Carvalho, Rita, Conde, Inês, Oliveira, Mónica, Gomes, Madalena, Pinto, Marta T., Pereira, Pedro, Pimentel, José, Souza, Cristiano, Marques, Márcia M. C., Duval da Silva, Vinícius, Barroso, Alison, Preto, Daniel, Cameselle-Teijeiro, Jorge F., Schmitt, Fernando, Ribeiro, Ana Sofia, Paredes, Joana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695320/
https://www.ncbi.nlm.nih.gov/pubmed/33182375
http://dx.doi.org/10.3390/cells9112442