Changes in Striatal Medium Spiny Neuron Morphology Resulting from Dopamine Depletion Are Reversible

The classical motor symptoms of Parkinson’s disease (PD) are caused by degeneration of dopaminergic neurons in the substantia nigra, which is followed by secondary dendritic pruning and spine loss at striatal medium spiny neurons (MSN). We hypothesize that these morphological changes at MSN underlie...

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Detalles Bibliográficos
Autores principales: Witzig, Victoria Sofie, Komnig, Daniel, Falkenburger, Björn H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695336/
https://www.ncbi.nlm.nih.gov/pubmed/33182316
http://dx.doi.org/10.3390/cells9112441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695336/
https://www.ncbi.nlm.nih.gov/pubmed/33182316
http://dx.doi.org/10.3390/cells9112441

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