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Association of Alzheimer’s disease risk variants on the PICALM gene with PICALM expression, core biomarkers, and feature neurodegeneration

It is still unclear how PICALM mutations influence the risk of Alzheimer’s disease (AD). We tested the association of AD risk variants on the PICALM gene with PICALM expression and AD feature endophenotypes. Bioinformatic methods were used to annotate the functionalities and to select the tag single...

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Detalles Bibliográficos
Autores principales: Xu, Wei, Tan, Chen-Chen, Cao, Xi-Peng, Tan, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695360/
https://www.ncbi.nlm.nih.gov/pubmed/33170153
http://dx.doi.org/10.18632/aging.103814