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Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE(2) pathway in non-small cell lung cancer

Radiotherapy is an effective treatment for non-small cell lung cancer (NSCLC). However, irradiated, dying tumor cells generate potent growth stimulatory signals during radiotherapy that promote the repopulation of adjacent surviving tumor cells to cause tumor recurrence. We investigated the function...

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Detalles Bibliográficos
Autores principales: Zhao, Minghui, Wang, Yiwei, Zhao, Yucui, He, Sijia, Zhao, Ruyi, Song, Yanwei, Cheng, Jin, Gong, Yanping, Xie, Jianzhu, Wang, Yulan, Hu, Binjie, Tian, Ling, Huang, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695367/
https://www.ncbi.nlm.nih.gov/pubmed/33180744
http://dx.doi.org/10.18632/aging.103984