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Caspase-3 knockout attenuates radiation-induced tumor repopulation via impairing the ATM/p53/Cox-2/PGE(2) pathway in non-small cell lung cancer
Radiotherapy is an effective treatment for non-small cell lung cancer (NSCLC). However, irradiated, dying tumor cells generate potent growth stimulatory signals during radiotherapy that promote the repopulation of adjacent surviving tumor cells to cause tumor recurrence. We investigated the function...
Autores principales: | Zhao, Minghui, Wang, Yiwei, Zhao, Yucui, He, Sijia, Zhao, Ruyi, Song, Yanwei, Cheng, Jin, Gong, Yanping, Xie, Jianzhu, Wang, Yulan, Hu, Binjie, Tian, Ling, Huang, Qian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695367/ https://www.ncbi.nlm.nih.gov/pubmed/33180744 http://dx.doi.org/10.18632/aging.103984 |
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