Dexmedetomidine inhibits inflammatory response and autophagy through the circLrp1b/miR-27a-3p/Dram2 pathway in a rat model of traumatic brain injury

Circular RNAs (circRNAs) have a regulatory function on inflammation and autophagy, of which rno-circRNA_010705 (circLrp1b) appears to be significantly up-regulated following traumatic brain injury (TBI). Dexmedetomidine (DEX) shows improvement effects in TBI by inhibiting NLRP3/caspase-1. However, w...

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Detalles Bibliográficos
Autores principales: Li, Hengchang, Lu, Chengxiang, Yao, Wenfei, Xu, Lixin, Zhou, Jun, Zheng, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695368/
https://www.ncbi.nlm.nih.gov/pubmed/33147167
http://dx.doi.org/10.18632/aging.103975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695368/
https://www.ncbi.nlm.nih.gov/pubmed/33147167
http://dx.doi.org/10.18632/aging.103975

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