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Mimetics of extra virgin olive oil phenols with anti-cancer stem cell activity

The extra virgin olive oil (EVOO) dihydroxy-phenol oleacein is a natural inhibitor of multiple metabolic and epigenetic enzymes capable of suppressing the functional traits of cancer stem cells (CSC). Here, we used a natural product-inspired drug discovery approach to identify new compounds that phe...

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Detalles Bibliográficos
Autores principales: Cuyàs, Elisabet, Gumuzio, Juan, Lozano-Sánchez, Jesús, Segura-Carretero, Antonio, Verdura, Sara, Bosch-Barrera, Joaquim, Martin-Castillo, Begoña, Nonell-Canals, Alfons, Llebaria, Amadeu, Cabello, Silvia, Serra, Carme, Sanchez-Martinez, Melchor, Martin, Ángel G., Menendez, Javier A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695371/
https://www.ncbi.nlm.nih.gov/pubmed/33168787
http://dx.doi.org/10.18632/aging.202154