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The horse as a natural model to study reproductive aging-induced aneuploidy and weakened centromeric cohesion in oocytes

Aneuploidy of meiotic origin is a major contributor to age-related subfertility and an increased risk of miscarriage in women. Although age-related aneuploidy has been studied in rodents, the mare may be a more appropriate animal model to study reproductive aging. Similar to women, aged mares show r...

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Detalles Bibliográficos
Autores principales: Rizzo, Marilena, du Preez, Nikola, Ducheyne, Kaatje D., Deelen, Claudia, Beitsma, Mabel M., Stout, Tom A. E., de Ruijter-Villani, Marta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695376/
https://www.ncbi.nlm.nih.gov/pubmed/33139583
http://dx.doi.org/10.18632/aging.104159