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The horse as a natural model to study reproductive aging-induced aneuploidy and weakened centromeric cohesion in oocytes
Aneuploidy of meiotic origin is a major contributor to age-related subfertility and an increased risk of miscarriage in women. Although age-related aneuploidy has been studied in rodents, the mare may be a more appropriate animal model to study reproductive aging. Similar to women, aged mares show r...
Autores principales: | Rizzo, Marilena, du Preez, Nikola, Ducheyne, Kaatje D., Deelen, Claudia, Beitsma, Mabel M., Stout, Tom A. E., de Ruijter-Villani, Marta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7695376/ https://www.ncbi.nlm.nih.gov/pubmed/33139583 http://dx.doi.org/10.18632/aging.104159 |
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